Chronic fatigue syndrome. 1: Etiology and pathogenesis.
Farrar, D J, Locke, S E, Kantrowitz, F G·Behavioral medicine (Washington, D.C.)·1995
ME/CFS is a serious illness that causes extreme tiredness and many other symptoms, but doctors don't yet fully understand what causes it or how to treat it best. This review looks at research about what might be happening in the body—including problems with the immune system and stress hormone regulation—but notes that no single explanation has been proven. Right now, treatment approaches are based on guesses rather than solid evidence, and we need better ways to identify which patients have which type of ME/CFS.