ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

121–140 of 1,205 studies

E0 ConsensusReviewPEM not requiredReview-Narrative

Chronic pain and fatigue syndromes: overlapping clinical and neuroendocrine features and potential pathogenic mechanisms.

Clauw, D J, Chrousos, G P·Neuroimmunomodulation·1997

This review examines fibromyalgia and chronic fatigue syndrome, two conditions with overlapping symptoms of pain and exhaustion that have been described throughout medical history under different names. The authors propose that both conditions stem from problems in the central nervous system—the brain and spinal cord—particularly in areas that control hormone levels, pain sensing, and automatic body functions. They suggest that immune system changes seen in these conditions are side effects rather than root causes.

Autonomic Nervous SystemImmune System

E0 ConsensusReviewPEM not requiredReview-Narrative

Chronic fatigue syndrome. 1: Etiology and pathogenesis.

Farrar, D J, Locke, S E, Kantrowitz, F G·Behavioral medicine (Washington, D.C.)·1995

ME/CFS is a serious illness that causes extreme tiredness and many other symptoms, but doctors don't yet fully understand what causes it or how to treat it best. This review looks at research about what might be happening in the body—including problems with the immune system and stress hormone regulation—but notes that no single explanation has been proven. Right now, treatment approaches are based on guesses rather than solid evidence, and we need better ways to identify which patients have which type of ME/CFS.

Evidence Atlas

Evidence browser

Chronic pain and fatigue syndromes: overlapping clinical and neuroendocrine features and potential pathogenic mechanisms.

Chronic fatigue syndrome. 1: Etiology and pathogenesis.

Pathogenic tracks in fatigue syndromes.

Clinical correlates of infection with human herpesvirus-6.

Studies of herpesvirus infection in chronic fatigue syndrome.

The pathophysiology of chronic fatigue syndrome: confirmations, contradictions, and conjectures.

Serologic and immunologic responses in chronic fatigue syndrome with emphasis on the Epstein-Barr virus.

Review of laboratory findings for patients with chronic fatigue syndrome.

An overview of chronic fatigue syndrome.

Effects of Qiye Shen'an Pian Combined with Glutamate and Vitamin B1 on Fatigue State, Immune Function and Quality of Life in Patients with Chronic Fatigue Syndrome.

[Bamboo-based medicinal moxibustion for chronic fatigue syndrome: a randomized controlled trial].

Achieving symptom relief in patients with myalgic encephalomyelitis by targeting the neuro-immune interface and optimizing disease tolerance.

[Clinical research of auricular gold-needle therapy in treatment of chronic fatigue syndrome of qi deficiency constitution].

[Acupuncture in the treatment of chronic fatigue syndrome based on "interaction of brain and kidney" in TCM: a randomized controlled trial].

Rituximab for Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

B-Lymphocyte Depletion in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.

Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment.

Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial.

Cytokine signature associated with disease severity in chronic fatigue syndrome patients

Intermittent and graded exercise effects on NK cell degranulation markers LAMP-1/LAMP-2 and CD8+CD38+ in chronic fatigue syndrome/myalgic encephalomyelitis.

Curated Collections

Neuroinflammation Evidence

Metabolism & Mitochondria

Biomarkers

PEM-Specific Research