ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

441–460 of 1,186 studies

E2 ModerateCohortPEM not requiredObservational

Effect of supplement with lactic-acid producing bacteria on fatigue and physical activity in patients with chronic fatigue syndrome.

Sullivan, Asa, Nord, Carl E, Evengård, Birgitta·Nutrition journal·2009

This small study tested whether specific probiotic bacteria (live microorganisms that may benefit gut health) could reduce fatigue and improve physical activity in ME/CFS patients. Fifteen patients took probiotics for 4 weeks and were monitored for changes in fatigue, physical activity, and cognitive function. While some patients reported feeling better overall, the study did not find significant improvements in fatigue or activity levels, though cognitive function did improve.

Immune SystemGut Microbiome

E2 ModerateCohortPEM not requiredCase-Control

Molecular study of receptor for advanced glycation endproduct gene promoter and identification of specific HLA haplotypes possibly involved in chronic fatigue syndrome.

Carlo-Stella, N, Bozzini, S, De Silvestri, A et al.·International journal of immunopathology and pharmacology·2009

This study looked at two genes related to inflammation in 75 Italian ME/CFS patients and compared them to 141 healthy controls. The researchers found that certain genetic variations in the RAGE gene and immune system genes called HLA were more common in ME/CFS patients, suggesting these genetic differences might increase risk for the condition. The findings suggest ME/CFS may involve inherited factors that affect how the immune system responds.

Evidence Atlas

Evidence browser

Effect of supplement with lactic-acid producing bacteria on fatigue and physical activity in patients with chronic fatigue syndrome.

Molecular study of receptor for advanced glycation endproduct gene promoter and identification of specific HLA haplotypes possibly involved in chronic fatigue syndrome.

Plasma cytokines in women with chronic fatigue syndrome.

Vitamin D metabolites as clinical markers in autoimmune and chronic disease.

An angiotensin-1 converting enzyme polymorphism is associated with allostatic load mediated by C-reactive protein, interleukin-6 and cortisol.

Anticardiolipin antibodies in the sera of patients with diagnosed chronic fatigue syndrome.

Autoantibodies, polymorphisms in the serotonin pathway, and human leukocyte antigen class II alleles in chronic fatigue syndrome: are they associated with age at onset and specific symptoms?

Association of peripheral inflammatory markers with chronic fatigue in a population-based sample.

Detection of herpesviruses and parvovirus B19 in gastric and intestinal mucosa of chronic fatigue syndrome patients.

Low-grade inflammation and arterial wave reflection in patients with chronic fatigue syndrome.

Evidence for T-helper 2 shift and association with illness parameters in chronic fatigue syndrome (CFS).

Chronic fatigue syndrome after human parvovirus B19 infection without persistent viremia.

Glucocorticoid sensitivity of immune cells in severely fatigued adolescent girls: a longitudinal study.

A longitudinal study of the relationship between psychological distress and recurrence of upper respiratory tract infections in chronic fatigue syndrome.

Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria.

An IgM-mediated immune response directed against nitro-bovine serum albumin (nitro-BSA) in chronic fatigue syndrome (CFS) and major depression: evidence that nitrosative stress is another factor underpinning the comorbidity between major depression and CFS.

Immunoassay with cytomegalovirus early antigens from gene products p52 and CM2 (UL44 and UL57) detects active infection in patients with chronic fatigue syndrome.

Alterations in diurnal salivary cortisol rhythm in a population-based sample of cases with chronic fatigue syndrome.

Lower frequency of IL-17F sequence variant (His161Arg) in chronic fatigue syndrome patients.

Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability.

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Neuroinflammation Evidence

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