ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

641–660 of 1,186 studies

E3 PreliminaryDiagnosticPEM unclearMethods-Paper

Measurement of Genetic Variations in ME/CFS Patients in the IDO2 Gene Encoding an Enzyme Metabolizing Tryptophan.

Edgar, Christina D, Blair, Anna, Tate, Warren P·Methods in molecular biology (Clifton, N.J.)·2025

This study looked at variations in a specific gene called IDO2 that controls an enzyme involved in breaking down tryptophan, an amino acid in our bodies. The researchers compared how often these genetic variations appear in ME/CFS patients versus healthy people, to see if certain variations might make someone more vulnerable to developing ME/CFS after a triggering event like a viral infection. They developed a straightforward laboratory technique to identify five common mutations in this gene.

Evidence Atlas

Evidence browser

Measurement of Genetic Variations in ME/CFS Patients in the IDO2 Gene Encoding an Enzyme Metabolizing Tryptophan.

Epstein-Barr virus and the origin of frailty and fatigue: A two-sample multivariable bidirectional Mendelian randomization study.

Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS.

The Gut-Brain-Immune Axis in Environmental Sensitivity Illnesses: Microbiome-Centered Narrative Review of Fibromyalgia Syndrome, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, and Multiple Chemical Sensitivity.

A network medicine approach to investigating ME/CFS pathogenesis in severely ill patients: a pilot study.

Using the Ratio of Phosphorylated to Non-phosphorylated Forms of Stress Kinase PKR as a Potential Diagnostic Test for ME/CFS.

Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome-a clinical pilot study.

Long COVID-19 autoantibodies and their potential effect on fertility.

Proposed Mechanistic Axis of Infections and mTOR Hyperactivation: A Multidisciplinary Review of Immune, Rheumatologic, and Psychiatric Links.

Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS.

Dysregulation of tetrahydrobiopterin metabolism in myalgic encephalomyelitis/chronic fatigue syndrome by pentose phosphate pathway.

What Makes It Tick: Exploring the Mechanisms of Post-treatment Lyme Disease Syndrome.

Long Covid.

Novel characterization of endogenous transient receptor potential melastatin 3 ion channels from Gulf War Illness participants.

Lacticaseibacillus rhamnosus Strains for Alleviation of Irritable Bowel Disease and Chronic Fatigue Syndrome.

Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome.

Potential pathophysiological role of the ion channel TRPM3 in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and the therapeutic effect of low-dose naltrexone.

Mast cells in the autonomic nervous system and potential role in disorders with dysautonomia and neuroinflammation.

Over-Representation of Torque Teno Mini Virus 9 in a Subgroup of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study.

Effect of Licorice polysaccharides before and after honey-processing on improving chronic fatigue syndrome and its mechanism.

Curated Collections

Neuroinflammation Evidence

Metabolism & Mitochondria

Biomarkers

PEM-Specific Research