ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

301–320 of 349 studies

E3 PreliminaryReviewPEM not requiredReview-Narrative

Can sustained arousal explain the Chronic Fatigue Syndrome?

Wyller, Vegard B, Eriksen, Hege R, Malterud, Kirsti·Behavioral and brain functions : BBF·2009

This study proposes that ME/CFS may be caused by the body getting stuck in a constant state of high alert, similar to being continuously stressed. This sustained arousal could develop after infections or emotional stress, especially in people with certain genetic traits or personality types. The researchers suggest this constant activation creates harmful cycles affecting the immune system, hormones, muscles, and thinking—ultimately leading to the overwhelming fatigue that defines ME/CFS.

Autonomic Nervous SystemImmune System

E3 PreliminaryReviewPEM not requiredReview-Narrative

Pathogenic mechanisms of idiopathic nonallergic rhinitis.

Baraniuk, James N·The World Allergy Organization journal·2009

This study examines why some people develop chronic nasal symptoms like congestion and runny nose that don't have an obvious allergic cause. Researchers found that this condition may actually involve several different problems: structural issues in the nose, nerve sensitivity problems, and autonomic nervous system dysfunction—the same type of nervous system problem found in ME/CFS.

Evidence Atlas

Evidence browser

Can sustained arousal explain the Chronic Fatigue Syndrome?

Pathogenic mechanisms of idiopathic nonallergic rhinitis.

POTS versus deconditioning: the same or different?

Orthostatic panic attacks among Vietnamese refugees.

Abnormal thermoregulatory responses in adolescents with chronic fatigue syndrome: relation to clinical symptoms.

Treatment of chronic fatigue and orthostatic intolerance with propranolol.

[School phobia and childhood chronic fatigue syndrome (CCFS)].

[Autonomic function and child chronic fatigue syndrome].

Sympathomimetic amine therapy may improve refractory gastroparesis similar to its effect on chronic pelvic pain--case report.

[Evaluation of fatigue by using acceleration plethysmography].

Cardiovascular systemic regulation by plantar surface stimulation.

Search for disease-specific cardiovascular reactivity patterns: developing the methodology.

Dysautonomia in chronic fatigue syndrome: facts, hypotheses, implications.

The effect of brief exercise cessation on pain, fatigue, and mood symptom development in healthy, fit individuals.

Physiology and pathophysiology of the 5-HT3 receptor.

Midodrine treatment for chronic fatigue syndrome.

Acetylcholine mediated vasodilatation in the microcirculation of patients with chronic fatigue syndrome.

Fainting freshmen and sinking sophomores: cardiovascular issues of the adolescent.

The head-up tilt test in the diagnosis and management of chronic fatigue syndrome.

Case reports and review of Postural Orthostatic Tachycardia syndrome (POTS).

Curated Collections

Neuroinflammation Evidence

Metabolism & Mitochondria

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