ME/CFS Evidence Browser — Classified Studies on Myalgic Encephalomyelitis

361–380 of 1,185 studies

E2 ModerateCohortPEM not requiredCase-Control

Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome.

Rajeevan, Mangalathu S, Dimulescu, Irina, Murray, Janna et al.·Human immunology·2015

Researchers compared the genes of 50 people with ME/CFS to 121 healthy people to look for differences in genes related to immune system and inflammation. They found 32 genetic differences associated with ME/CFS, particularly in genes controlling how the body's natural defense system works. These findings suggest that problems with immune activation may play a role in ME/CFS.

Evidence Atlas

Evidence browser

Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome.

Increased expression of activation antigens on CD8+ T lymphocytes in Myalgic Encephalomyelitis/chronic fatigue syndrome: inverse associations with lowered CD19+ expression and CD4+/CD8+ ratio, but no associations with (auto)immune, leaky gut, oxidative and nitrosative stress biomarkers.

Increased Risk of Chronic Fatigue Syndrome Following Atopy: A Population-Based Study.

Role of polymorphisms of inducible nitric oxide synthase and endothelial nitric oxide synthase in idiopathic environmental intolerances.

A Novel Anxiety and Affective Spectrum Disorder of Mind and Body-The ALPIM (Anxiety-Laxity-Pain-Immune-Mood) Syndrome: A Preliminary Report.

Longitudinal analysis of immune abnormalities in varying severities of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients.

Serum Immune Proteins in Moderate and Severe Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients.

Plasma cytokine expression in adolescent chronic fatigue syndrome.

Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome.

A new case definition of Neuro-Inflammatory and Oxidative Fatigue (NIOF), a neuroprogressive disorder, formerly known as chronic fatigue syndrome or Myalgic Encephalomyelitis: results of multivariate pattern recognition methods and external validation by neuro-immune biomarkers.

Cytokines in the cerebrospinal fluids of patients with chronic fatigue syndrome/myalgic encephalomyelitis.

Distinct plasma immune signatures in ME/CFS are present early in the course of illness.

Cytokine expression provides clues to the pathophysiology of Gulf War illness and myalgic encephalomyelitis.

Chronic fatigue syndrome: Features of a population of patients from northern Italy.

Sympathetic activation is associated with increased IL-6, but not CRP in the absence of obesity: lessons from postural tachycardia syndrome and obesity.

[FREQUENCY OF IMMUNOGLOBULIN E DEFICIENCY AMONG PATIENTS WITH IMMUNODEPENDENT DISORDERS].

Attenuation of autoimmune responses to oxidative specific epitopes, but not nitroso-adducts, is associated with a better clinical outcome in Myalgic Encephalomyelitis/chronic fatigue syndrome.

Role of adaptive and innate immune cells in chronic fatigue syndrome/myalgic encephalomyelitis.

Dimensions of pure chronic fatigue: psychophysical, cognitive and biological correlates in the chronic fatigue syndrome.

Evidence for the existence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with and without abdominal discomfort (irritable bowel) syndrome.

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Neuroinflammation Evidence

Metabolism & Mitochondria

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PEM-Specific Research